Siavash Shahbazi Nia | Texas Tech University Health Sciences Center

Pharmaceutical Sciences

shahbazi_nia
  • Graduate Student / Research Assistant

Lab Phone: 806-414-9368
E-Mail: Siavash.Shahbazi@ttuhsc.edu
Mail Address: 1300 S Coulter
Amarillo, TX 79106-1712

Biography

Siavash Shahbazi Nia completed his Doctor of Pharmacy (PharmD) degree from Rajiv Gandhi University of Health Sciences, Karnataka, India, in 2018. He joined the Graduate Program in Pharmaceutical Sciences as a Doctor of Philosophy (PhD) student in June of 2019, and is presently working in the laboratory of Dr. Nadezhda German with the Department of Pharmaceutical Sciences.

Education:

  • PharmD: Rajiv Gandhi University of Health Sciences, Karnataka, India, 2018

Research Interests:

Structure activity relationship approaches and application for design and synthesis of novel compounds with proposed antimicrobial activity and their biological appraisal.

Publications:

   Before Admission to GPPS:

  • Siavash Shahbazi Nia, Shobha Rani R. Hiremath, Shankar Prasad. Assessment of Antimicrobial Use Pattern Using World Health Organization Prescribing Indicators at a Tertiary Hospital: A Prospective, Observational study. J App Pharm Sci. 2018;8(06):132-8.
  • Siavash Shahbazi Nia, Shadan Modaresahmadi, Vithya Thirumoorthi, Qaisar Anwar, Shankar Prasad. Multi-drug resistant poly-microbial bacteremia and sepsis: a rare case report. Asian J Pharm Clin Res. 2018;11(9):5-8.
  • Armin Eisa Zaei, Siavash Shahbazi Nia, Shadan Modaresahmadi. Assessment of Adverse Drug Reactions Associated with Antihypertensive Agents and Antibiotics at a Tertiary Care Hospital. Asian Journal of Pharmaceutical Research and Health Care. 2018;10(2):54-59.
  • Siavash Shahbazi Nia, Shadan Modaresahmadi, Armin Eisa Zaei. Distinguishing adverse drug reactions, the noxious effects of medicines at a tertiary care hospital. Int J Pharma Investig. 2018;8:69-73.

   After Admission to GPPS:

  • Shahbazi Nia S, Hossain MA, Ji G, Jonnalagadda SK, Obeng S, Rahman MA, Sifat AE, Nozohouri S, Blackwell C, Patel D, Thompson J, Runyon S, Hiranita T, McCurdy CR, McMahon L, Abbruscato TJ, Trippier PC, Neugebauer V, German NA. Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands. Eur J Med Chem. 2023 Jun 5; 254:115309. Epub 2023 Mar 29.
  • Lahooti B, Akwii RG, Patel D, Shahbazi Nia S, Lamprou M, Madadi M, Abbruscato TJ, Astrinidis A, Bickel U, Al-Ahmad A, German NA, Mattheolabakis G, Mikelis CM. Endothelial-Specific Targeting of RhoA Signaling via CD31 Antibody-Conjugated Nanoparticles. J Pharmacol Exp Ther. 2023 Apr; 385(1):35-49. Epub 2023 Feb 6.

Presentations:

   Before Admission to GPPS:

  • Siavash Shahbazi Nia, Shadan Modaresahmadi, Vithya Thirumoorthi, Qaisar Anwar, Shankar Prasad. “A case study on antibiotic-resistant sepsis at a tertiary care hospital”. 8th Asian Association of Schools of Pharmacy Conference, Mysore, India; October 2017.

   After Admission to GPPS:

  • Siavash Shahbazi Nia, Mohammad Anwar Hossain, Samuel Obeng, Saeideh Nozohouri, Dhavalkumar Patel, Raja Reddy Kalem, Guangchen Ji, Ali Ehsan Sifat, Takato Hiranita, Thomas J. Abbruscato, Paul C. Trippier, William Putnam, Volker Neugebauer, Nadezhda A. German. "Selective KOR Antagonists, Novel Candidates for Treatment of Neuropathic Pain".  Student Research Week, TTUHSC Graduate School of Biomedical Sciences, Lubbock; March 2022.
  • Podium Presentation: Siavash Shahbazi Nia, Mohammad A Hossain, Guangchen Ji, Samuel Obeng, Saeideh Nozohouri, Dhavalkumar Patel, Raja R Kalem, Sravan Jonnalagadda, Ali E Sifat, Takato Hiranita, Thomas J Abbruscato, Paul C Trippier, William Putnam, Volker Neugebauer, and Nadezhda A German. "Selective Kappa Opioid Receptor Antagonists as Potential Candidates for Treatment of Neuropathic Pain, Eliminating Opioid-induced Addiction". Behavior, Biology, and Chemistry (BBC): Translational Research in Addiction, University of Texas Health Science Center at San Antonio (UTHSCSA), BBC 2022 Annual Meeting, San Antonio, Texas, February 2022.
  • Siavash Shahbazi Nia, Mohammad Anwar Hossain, Guangchen Ji, Ali Ehsan Sifat, Thomas J. Abbruscato, Volker Neugebauer, Nadezhda A. German. "Management of neuropathic pain using novel KOP-antagonists ". American Chemical Society (ACS), Atlanta, GA (virtual); August 2021.
  • Siavash Shahbazi Nia, Mohammad Anwar Hossain, Guangchen J, Ali Ehsan Sifat, Thomas J. Abbruscato, Volker Neugebauer, Nadezhda A. German. "Design and Synthesis of Gliotoxin Analogs as Selective KOR Antagonists for Treatment of Chronic Pain". Research Days, TTUHSC Jerry H Hodge School of Pharmacy Amarillo (virtual); June 2021.
  • Siavash Shahbazi Nia, Mohammad Anwar Hossain, Guangchen Ji, Ali Ehsan Sifat, Thomas J. Abbruscato. “Design and synthesis of novel KOP receptor antagonists, a treatment option for neuropathic pain". Fifth Annual Research Symposium: Aging-Related Health Issues and Alzheimer’s Disease, Center of Excellence for Translational Neuroscience and Therapeutics (CTNT) and Garrison Institute on Aging (GIA), TTUHSC in Lubbock (virtual); May 2021.
  • Siavash Shahbazi Nia, Nadezhda A. German. "Novel Selective Kappa-Opioid Ligands as Modulators of Pain Responses". Texas Pain Research Highlights 2021, Texas Pain Research Consortium, virtual; April 2021.

Seminars:

  • 02/03/2023 "Impact of structural modification on the affinity and metabolic stability of novel KOR ligands"
  • 11/19/2021 "Development of a Novel Class of Selective Sigma-1 Receptor Agonists as Antidepressants" [Oral Qualifying Exam, public presentation counted as Seminar credit]
  • 01/15/2021 “Design and Synthesis of Novel Small-Molecule Ligands to Target Opioid Receptors”

Awards/Scholarships:

  • Travel Award; Behavior, Biology, and Chemistry (BBC): Translational Research in Addiction; University of Texas Health Science Center at San Antonio (UTHSCSA), BBC 2022 Annual Meeting, San Antonio, Texas; February 2022.
  • Best Poster Award, Graduate/Undergraduate Student Level, Clinical Category, Fifth Annual Research Symposium: Aging-Related Health Issues and Alzheimer’s Disease, TTUHSC Center of Excellence for Translational Neuroscience and Therapeutics (CTNT) and Garrison Institute on Aging (GIA), Lubbock (virtual); May 2021.

Memberships:

  • Graduate Student Association in Amarillo (GSAA), TTUHSC, 2019-present.
  • American Chemical Society (ACS), 2019-present.
  • International Journal of Medicine and Public Health (IJMEDPH) – Editorial Board Member, 2018-present.
  • Member of International Society for Pharmacoeconomics and Outcomes Research (ISPOR), 2016-2018.