Md. Sariful Islam Howlader | Texas Tech University Health Sciences Center

Md. Sariful Islam Howlader

Pharmaceutical Sciences

howlader
  • Graduate Student / Research Assistant

Lab Phone: 806-414-9329
E-Mail: mdhowlad@ttuhsc.edu
Mail Address: 1406 S Coulter
Amarillo, TX 79106-1786

Biography

Md. Sariful Islam Howlader completed his Bachelor of Pharmacy (BPharm) degree from Khulna University at Khulna, Bangladesh in 2010. After completing his BPharm from Khulna University, he worked as a senior lecturer in the Department of Pharmacy at World University of Bangladesh. He then completed his Master of Science (MS) degree in Chemistry from Tennessee Technological University at Cookeville, Tennessee in 2019. He joined the Graduate Program in Pharmaceutical Sciences as a Doctor of Philosophy (PhD) student in August of 2020, and is presently working in the laboratory of Dr. Hiranmoy Das with the Department of Pharmaceutical Sciences.

Education:

MS: Chemistry, Tennessee Technological University, Cookeville, Tennessee, 2019
BPharm: Khulna University, Khulna, Bangladesh, 2010

Research Interests:

Stem-cell therapy, cardiovascular disease, atherosclerosis.

Publications:

   Before Admission to GPPS:

  • Siraj MA, Howlader MS, Islam MA, Irin T, Simal-Gandara J. Regulation of the redox signaling and inflammation by Terminalia myriocarpa leaves and the predictive interactions of its major metabolites with iNOS and NF-ĸB. Journal of Ethnopharmacology. 2021 Nov 15;280:114459. Epub 2021 Jul 31
  • Siraj MA, Howlader MSI, Rahaman MS, Shilpi JA, Seidel V. Antinociceptive and sedative activity of Vernonia patula and predictive interactions of its phenolic compounds with the cannabinoid type 1 receptor. Phytother Res. 2020 Oct 29. Online ahead of print.
  • Howlader MSI, Siraj MA, Dey SK, Hira A, Ahmed A, and Hossain H. Ficus hispida Bark Extract Prevents Nociception, Inflammation, and CNS Stimulation in Experimental Animal Model. Evid Based Complement Alternat Med. 2017;2017:7390359. Epub 2017 Apr 12.
  • Laboni FR, Afsari F, Howlader MSI, Labu ZK, Julie AS. Thrombolytic and membrane stabilizing activities of ethanolic extract of local medicinal plant Murraya paniculata. (Family: Rutaceae). Journal of Pharmacognosy and Phytochemistry. 2015;4(2):17-20.
  • Labu ZK, Laboni FR, Mamun MMA, Howlader MSI. Antidiarrhoeal Activity and Total Tannin Content of Ethanolic Leaf Extract of Codiaeum variegatum. Dhaka Univ. J. Pharm. Sci. 2015 Jun 18;14(1):87-90.
  • Dey SK, Hira A, Howlader MSI, Ahmed A, Hossain H, Jahan IJ. Antioxidant and antidiarrheal activities of ethanol extract of Ardisia elliptica fruits. Pharmaceutical Biology. 2014;52(2):213-20. Epub 2013 Oct 4.
  • Hira A, Dey SK, Howlader MSI, Ahmed A, Hossain H, Jahan IJ. Anti-inflammatory and antioxidant activities of ethanolic extract of aerial parts of Vernonia patula (Dryand.) Merr. Asian Pacific Journal of Tropical Biomedicine. 2013 Oct;3(10):798-805. Epub 2013 Sep 4.
  • Hossain H, Jahan IJ, Howlader MSI, Shilpi JA, Dey SK, Hira A. Anti-inflammatory and antioxidant activities of ethanolic leaf extract of Brownlowia tersa (L.) Kosterm. Oriental Pharmacy and Experimental Medicine. 2013 Mar 5;13(3):181-189.
  • Hossain H, Ismet Ara Jahan, Howlader MSI, Dey SK, Hira A, Ahmed A. Phytochemical Screening and Anti-Nociceptive Properties of the Ethanolic Leaf Extract of Trema Cannabina Lour. Advanced Pharmaceutical Bulletin. 2013 Feb 7;3(1):103-108. Epub 2013 Feb 7.
  • Dey SK, Hira A, Ahmed A, Howlader MSI, Khatun A, Rahman M, Siraj MA. Phytochemical screening and pharmacological activities of Entada Scandens seeds. International Journal of Applied Research in Natural Products. 2013;6(1):20-26.
  • Howlader MSI, Ahmed MJ, Kabir AN, Uddin MG, Hossain MK. Antibacterial, cytotoxic, analgesic and diuretic activities of Rhizophora mucronata Lam. bark. Indian Journal of Natural Products and Resources. 2013;4(3):229-232.
  • Ahmed A, Howlader MSI, Dey SK, Hira A, Hossain H, Uddin MMN. Phytochemical screening and antibacterial activity of different fractions of Operculina turpethum root and leaf. Am. J. Sci. Ind. Res. 2013;4(2):167-172.
  • Hossain H, Howlader MSI, Dey SK, Hira A, Ahmed A. Antinociceptive and antidiarrhoeal activities of the ethanolic leaf extract of Tiliacora Acuminata LAM. Turkish Journal of Pharmaceutical Sciences. 2013;10 (3): 393-404.
  • Hossain H, Howlader MSI, Dey SK, Hira A, Ahmed A. Antinociceptive and antidiarrheal properties of the ethanolic extract of Manilkara zapota (Linn.) bark. International Journal of Pharmaceutical science and research. 2012 Dec 1; 3(12):4791-4795.
  • Hossain H, Howlader MSI, Shubhra Kanti Dey, Hira A, Ahmed A. Evaluation of Analgesic, Antidiarrhoeal and Cytotoxic activities of Ethanolic Extract of Bacopa monnieri (L). British Journal of Pharmaceutical Research. 2012 Nov 2; 2(3):188-196.
  • Howlader MSI**,** Dey SK, Hira A, Ahmed A, Hossain H. Antinociceptive and neuropharmacological activities of ethanolic extract of the fruits of Ficus hispida Linn. African Journal of Pharmacy and Pharmacology. 2012 Oct 31;6(40):2837-2844.
  • Howlader MSI, Rahman MM, Khalipha ABR, Rahman MM, Ahmed F. Antioxidant and Antidiarrhoeal Potentiality of Diospyros blancoi. International Journal of Pharmacology. 2012;8(5):403-409.
  • Howlader MSI, Hossain H, Dey SK, Hira A, Ahmed A. Evaluation of antinociceptive, antimicrobial and cytotoxic activities of ethanolic extract of Acacia nilotica leaves from Bangladesh. Pharmacology Online. 2012;2:73 – 81.
  • Howlader MSI, Dey SK, Hira A, Ahmed A. Evaluation of antinociceptive and antioxidant properties of the ethanolic extract of Sonneratia caseolaris leaves. Der Pharmacia Sinica. 2012;3(5):536-541.

   After Admission to GPPS:

  • Sarkar J, Das M, Howlader MSI, Prateeksha P, Barthels D, Das H. Epigallocatechin-3-gallate inhibits osteoclastic differentiation by modulating mitophagy and mitochondrial functions. Cell Death Dis. 2022 Oct 28; 13(10):908.
  • Barthels D, Prateeksha P, Nozohouri S, Villalba H, Zhang Y, Sharma S, Anderson S, Howlader MSI, Nambiar A, Abbruscato TJ, Das H. Dental Pulp-Derived Stem Cells Preserve Astrocyte Health During Induced Gliosis by Modulating Mitochondrial Activity and Functions. Cell Mol Neurobiol. 2022 Oct 6. Epub ahead of print.
  • Laha D, Sarkar J, Maity J, Pramanik A, Howlader MSI, Barthels D and Das H. Polyphenolic Compounds Inhibit Osteoclast Differentiation While Reducing Autophagy through Limiting ROS and the Mitochondrial Membrane Potential. Biomolecules. 2022 Sep 1; 12(9):1220.
  • Greene CJ, Anderson S, Barthels D, Howlader MSI, Kanji S, Sarkar J, Das H. DPSC Products Accelerate Wound Healing in Diabetic Mice through Induction of SMAD Molecules. Cells. 2022 Aug 4;11(15):2409.

Presentations:

   Before Admission to GPPS:

  • Howlader MSI, Zhan X. “Assembly of ASK1-MKK4/7-JNK3 kinase cascades”. 10th Annual Southeast Enzyme Conference, Georgia State University, Atlanta, Georgia; April 2019.
  • Howlader MSI, Zhan X. “Assembly of ASK1-MKK4/7-JNK3 kinase cascades”. 14th Annual Research and Creative Inquiry Day, Tennessee Technological University, Cookeville, Tennessee; April 2019.

   After Admission to GPPS:

  • INVITED SPEAKER:  Md Sariful Isla Howlader, Ripon Sarkar, Jaganmoy Sarkar, Hiranmoy Das. "The role of KLF2 in the regulation of rheumatoid arthritis". ­­Global Experts Meet on Nursing and Healthcare (GEMNR) 2023, mScholar Conferences, Paris, France (virtually); April 2023.
  • INVITED SPEAKER:  Md Sariful Islam Howlader, Ripon Sarkar, Hiranmoy Das. "KLF2 modulates the function and activity of mitochondria in osteoclast differentiation". The International Forum on Cell Science & Molecular Biology (CSMBFORUM2023), Valencia, Spain [virtual]; April 2023.
  • Md Sariful Islam Howlader, Hiranmoy Das. "KLF2 modulates mitochondrial activity and function in rheumatoid arthritis". Gordon Research Conference (GRC): Multi-Drug Efflux Systems GRC (Targeting the Mechanisms and Regulation of Transporters for Advancing Health During a Pandemic), Grand Galvez in Galveston, TX; March 2023.
  • PODIUM PRESENTATON:  Md Sariful Islam Howlader,  Hiranmoy Das. "Mitochondrial activity and function are modulated by KLF2 in rheumatoid arthritis". 35th Annual Student Research Week, TTUHSC Graduate School of Biomedical Sciences, Lubbock; Feb/Mar 2023.
  • INVITED SPEAKER:  Md Sariful Islam Howlader, Sarah Anderson, Carl J Greene, Derek Barthels, Hiranmoy Das. "DPSC Products Accelerate Wound Healing in Diabetic Mice through Induction of SMAD Molecules". PHARMAMEET2023, Porto, Portugal [virtually]; February 2023.
  • GUEST SPEAKER:  Md Sariful Islam Howlader, Sarah Anderson, Carl J Greene, Derek Barthels, Hiranmoy Das. “DPSC Products Accelerate Wound Healing in Diabetic Mice through Induction of SMAD Molecules”. Second International Conference on Advanced Cardiology [Allied Academies], Rome, Italy [virtual]; October 2022.
  • Md Sariful Islam Howlader, Hiranmoy Das. "Osteoclast Differentiation is Controlled by KLF2 through the Regulation of Mitochondrial Dysfunction". American Association of Pharmaceutical Scientists (AAPS) PharmSci 360, Boston, MA; October 2022.
  • INVITED SPEAKER: Md Sariful Islam Howlader, Ripon Sarkar, Hiranmoy Das. "Role of KLF2 in myeloid cells in controlling osteoclastogenesis process". Virtual Research Seminar Series, University of Illinois Chicago (UIC) Dept. of Ophthalmology & Visual Sciences, Chicago, IL; August 2022.
  • Md Sariful Islam Howlader, Ripon Sarkar, Hiranmoy Das. "KLF2 regulates osteoclast differentiation by modulating mitochondrial activity and function". 19th Annual Research Days, TTUHSC Jerry H Hodge School of Pharmacy, Office of Sciences in Amarillo, event at Lubbock, TX; June 2022.
  • Md. Sariful Islam Howlader, Ripon Sarkar, Hiranmoy Das. "KLF2 regulates osteoclast differentiation by modulating mitochondrial activity and function". Student Research Week, TTUHSC Graduate School of Biomedical Sciences, Lubbock; March 2022.

Seminars:

  • 09/16/2022 "Role of KLF2 in myeloid cells in controlling atherosclerosis" [Oral Qualifying Exam, presentation counted as Seminar credit]
  • 04/15/2022 "KLF2 regulates osteoclast differentiation by modulating mitochondrial activity and function"

Awards/Scholarships:

   Before Admission to GPPS:

  • Graduate Student Research Award, Tennessee Technological University, Cookeville, Tennessee, 2018.
  • Khulna University Merit Scholarship, 2009.
  • Khulna University Merit Scholarship, 2008.
  • Khulna University Merit Scholarship, 2007.
  • Secondary School Certificate, Gold Model Award, Sonali Bank, December 2002.

   After Admission to GPPS:

  • Registration Fee Waiver, Gordon Research Conferences (GRC): Multi-Drug Efflux Systems, Galveston, TX; March 2023. [selected Feb'23]
  • Travel Grant Award, Cayman Chemical Company, American Association of Pharmaceutical Scientists (AAPS) PharmSci 360, Boston, MA; October 2022.
  • Best Poster Award, Junior Graduate Student Category, 19th Annual Research Days, TTUHSC Jerry H Hodge School of Pharmacy, Office of Sciences in Amarillo, event at Lubbock, TX; June 2022.
  • Phonathon Endowed Scholarship, TTUHSC Student Government Association, February 2022 [to be applied graduating term].

Memberships:

  • Study Abroad Committee, The Honor Society of Phi Kappa Phi (International), TTUHSC Chapter, 2022-2024 [biennium].
  • The Honor Society of Phi Kappa Phi (International), TTUHSC Chapter, 2022-present.
  • American Association of Pharmaceutical Scientists (AAPS) Abstract Screening Committee (ASC), Track Chair, Discovery and Basic Research, April 2022 (for AAPS PharmSci 360, October 2022).
  • American Association of Colleges of Pharmacy (AACP), 2022-present.
  • American Association of Pharmaceutical Scientists (AAPS), 2021-present.
  • American Association of Pharmaceutical Scientists (AAPS) TTUHSC Student Chapter, 2021-present.
  • Graduate Student Association in Amarillo (GSAA), TTUHSC, 2020-present.
  • Graduate Chemistry Club (GCC), Tennessee Technological University, Cookeville, Tennessee, 2017-2019.