Bhagavathi Ramasubramanian

I attended Mumbai University, India where I received my BSC and MSC in Microbiology. I then worked as a Clinical Microbiologist. I had an opportunity to lead and operate a very busy Clinical lab. I was intrigued by the emerging antibiotic resistant infections and hence moved to USA to do research in this area. I obtained MS and PhD in Medical Microbiology at the Texas Tech University Health Sciences Center, Lubbock, TX. During my graduate studies I focused on gene regulation and genetics of Multidrug resistant (MDR) efflux pump, a mechanism by which bacteria become resistant to antibiotics.  I have extensive research laboratory experience in microbiology, biochemistry and molecular biology labs. I have worked for prestigious organizations such as UTMB, Galveston and Scott and White Healthcare, Temple TX.      

Later, I developed interest towards studying aging and neurological diseases and currently I am a Postdoctoral Research Associate in the lab of Dr. Hemachandra Reddy, Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX. My current research interests include:

1. Develop a rational basis for neuroprotective strategies to prevent the onset or slow the progression of Huntington’s disease. The main focus of this project is to generate and maintain colonies of transgenic Huntington’s disease mice. We will then determine protective effects of mitochondrial division inhibitor in these mouse models for Huntington’s disease. The outcome will provide new insights for therapeutics for Huntington’s disease.

2. We are also developing a diet from Chaya (tree spinach) leaves for diabetes using a mouse, in collaboration with researchers from Texas Tech University.  This project will elucidate the parameters and scope of the antidiabetic effects of Chaya using naturally occurring polygenic mouse model – TallyHo mice. The outcome of our findings will provide new insights about basic molecular mechanisms and translational aspects of Chaya against diabetes.

Outside the lab I enjoy music, photography and love to explore nature.