Dr. Sanjay Awasthi | Texas Tech University Health Sciences Center

Sanjay Awasthi, MD

Sanjay Awasthi

Sanjay Awasthi, MD

Professor, Department of Internal Medicine,
Division of Hematology & Oncology

 

Glutathione Chemistry and Biochemistry
Carcinogenesis
Antioxidants
Cancer Drug Development
p53 and Ralbp1 in Carcinogenesis

Basic Research
We have recently achieved complete suppression of malignancy in p53 knockout mice, never previously accomplished. This will directly impact nearly half of all cancer patients with respect to therapy and prevention.

  • Awasthi S., Podium, Indian Institute of Toxicological Research, India December 2018. 4HNE-Metabolism in toxicology.
  • Awasthi S., Podium, King George Medical University, Lucknow, India December 2018. Switching off carcinogenesis.
  • Awasthi S., Podium, 4HNE-Club, Vanderbilt University, November 2018.
    RALBP1 Modulation in Therapy of Cancer, Diabetes, Epilepsy and Poisoning.
  • Shanshal M, Tijani L, Hardwicke FL, Kaleem H, D'Cunha NC, Igid HP, Khan MS, Jones C, Awasthi S, Radhi S., Annual Meeting, American Society of Clinical Oncology (ASCO), 2017. A novel function of SMC1 as a transporter of xenobiotics.
  • Yendala R, Tijani L, Thein KZ, Igid HP, Shanshal M, Awasthi S, Hardwicke FL., Annual Meeting, American Society of Clinical Oncology (ASCO), 2017.
    A novel function of SMC1 as a transporter of xenobiotics.
  • Nagaprashantha LD, Singhal J, Chikara S, Gugiu G, Horne D, Awasthi S, Salgia R, Singhal SS. 2 '-Hydroxyflavanone induced changes in the proteomic profile of breast cancer cells. JOURNAL OF PROTEOMICS 2019;192:233-245.
  • Singhal J, Chikara S, Horne D, Salgia R, Awasthi S, Singhal SS. 2 '-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76. MOLECULAR CARCINOGENESIS 2018;57(12):1751-1762.
  • Igid HP, Thein KZ, Sultan A, Swarup S, Awasthi S, Jones C. A systematic review and meta-analysis of randomized controlled trials to evaluate the risk of hypophosphatemia, hypertension, and hematological toxicities in patients with cancer treated with regorafenib.. JOURNAL OF CLINICAL ONCOLOGY 2018;36(15).
  • Awasthi S. Effective prevention of cancer in p53 null mice by depleting Rlip.. JOURNAL OF CLINICAL ONCOLOGY 2018;36(15).
  • Awasthi S. Effective prevention of cancer in p53 null mice.. J Clin Oncol 2018;36(15 Suppl):e13540.